Baked Creamy Cajun Shrimp Casserole

Total Time: 1 hr Difficulty: Beginner
Savor the flavors of the South with this creamy Cajun shrimp casserole that’s perfect for any family dinner!
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There’s something undeniably comforting about tucking into a dish that layers tender seafood with creamy, spicy goodness—and that, my friends, is exactly what this Baked Creamy Cajun Shrimp Casserole delivers. I still remember the first time I stirred together a heap of sautéed bell peppers and onions with sweet corn and a velvety blend of mushroom soup and sour cream. The kitchen filled with the warm hum of bubbling cheese and spice, and by the time the shrimp, seasoned with a kiss of Cajun heat, joined the party, I was already sold. This casserole is more than a simple dinner; it’s a celebration of Southern-inspired flavors that feel like a hug in a baking dish.

As an enthusiastic home cook who’s always hunting for easy, crowd-pleasing recipes, I love how this casserole balances convenience with show-stopping taste. It’s a beginner-friendly bake that only takes about 20 minutes of prep and 30 minutes in the oven, yet it looks—and tastes—like a dish you’d order at a cozy seafood bistro. The bright pops of red and green peppers, the golden blanket of cheddar and Parmesan, and the gentle kick of Cajun seasoning all come together to create a meal that’s as beautiful on the table as it is on the palate. Gather your ingredients, invite your family or friends, and get ready for one of the most satisfying dinners you’ll whip up all week.

KEY INGREDIENTS IN BAKED CREAMY CAJUN SHRIMP CASSEROLE

Before diving into the cooking process, let’s talk about the stars of this recipe. Every ingredient plays an important role in building layers of texture, color, and flavor. From the spicy, succulent shrimp to the creamy cheese topping and the earthy notes of sautéed veggies, here’s how each component contributes to the magic of this casserole:

  • Large shrimp

These peeled and deveined gems bring a tender, succulent protein base that soaks up the bold Cajun seasoning. Their mild sweetness pairs perfectly with the creamy sauce.

  • Olive oil

A drizzle of olive oil helps the shrimp absorb the Cajun spices without drying out, and it adds a hint of fruity richness to the pan.

  • Cajun seasoning

A fragrant blend of paprika, garlic powder, onion powder, and a few secret spices that inject a gentle heat and distinctive Southern flair into every bite.

  • Butter

Melting in the skillet, butter creates a luscious coating for the onions, garlic, and peppers, lending a rich, silky texture to the vegetable base.

  • Onion

Finely chopped onion adds a sweet, aromatic depth when sautéed, forming the foundation of flavor for the creamy sauce.

  • Garlic

Minced garlic offers a punchy, savory note that elevates each spoonful, infusing the dish with its irresistible warmth.

  • Red bell pepper

Diced red peppers bring a vibrant color and crunchy sweetness that brightens up the rich casserole.

  • Green bell pepper

With its fresh, slightly grassy flavor, green bell pepper contrasts the red pepper beautifully and adds extra texture.

  • Frozen corn kernels

These little bursts of sweetness and poppy texture blend seamlessly into the sautéed veggies, providing playful contrast with each forkful.

  • Cream of mushroom soup

Acting as the creamy backbone, this soup incorporates an earthy, savory note while binding the rice and shrimp together.

  • Sour cream

Stirred into the soup, sour cream enhances the luscious mouthfeel and introduces a gentle tang that balances the spices.

  • Shredded cheddar cheese

A sharp, melty layer that blankets the top of the casserole, delivering that coveted golden, gooey finish.

  • Grated Parmesan cheese

Sprinkled alongside the cheddar, Parmesan contributes a nutty, salty bite that rounds out the cheesy topping.

  • Cooked rice

Steamed rice soaks up the creamy sauce, transforming this bake into a hearty, comforting main course.

  • Fresh parsley

Chopped parsley adds a final pop of green and a herby brightness that cuts through the richness.

  • Salt and pepper

These pantry staples are essential for bringing all the flavors into perfect harmony. Adjust to taste!

HOW TO MAKE BAKED CREAMY CAJUN SHRIMP CASSEROLE

Ready to get cooking? This is where all the delicious ingredients you’ve gathered come together. Follow these steps closely for a casserole that’s golden, bubbly, and packed with flavor.

1. Preheat your oven to 350°F (175°C). Grease a 9×13-inch baking dish with butter or nonstick spray to prevent sticking and ensure crisp edges.

2. In a medium bowl, toss the shrimp with olive oil and Cajun seasoning until each piece is thoroughly coated. Let them rest while you prepare the rest of the dish—this helps the flavors meld.

3. In a large skillet over medium heat, melt the butter. Add the chopped onion and minced garlic, then sauté until the onion becomes translucent and fragrant, about 3–4 minutes.

4. Stir in the diced red and green bell peppers. Cook until the peppers soften and release their natural sweetness, about 5 minutes, stirring occasionally.

5. Add the frozen corn kernels and let them cook for an additional 2–3 minutes, until heated through. This step brings out their sweet crunch.

6. Remove the skillet from heat. Stir in the cream of mushroom soup and sour cream, mixing thoroughly until you have a smooth, creamy sauce.

7. Fold in the cooked rice, making sure every grain is coated with the velvety sauce. Season with salt and pepper to taste.

8. Transfer half of the rice mixture to the prepared baking dish, spreading it out in an even layer to support the shrimp.

9. Arrange the seasoned shrimp over the rice layer, spacing them evenly for uniform cooking.

10. Sprinkle half of the shredded cheddar and Parmesan cheese over the shrimp, covering them with a cheesy blanket.

11. Top with the remaining rice mixture, smoothing it gently, then sprinkle the rest of the cheeses on top.

12. Cover the dish with foil and bake in the preheated oven for 20 minutes. This traps steam and ensures everything heats through without drying out.

13. Remove the foil and continue baking for an additional 10 minutes, or until the cheese on top is melted, golden, and bubbly.

14. Once baked, let the casserole cool slightly—about 5 minutes—before removing from the oven. This brief rest helps it set for cleaner slices.

15. Sprinkle with chopped fresh parsley, then serve warm and dig into your creamy Cajun shrimp masterpiece.

SERVING SUGGESTIONS FOR BAKED CREAMY CAJUN SHRIMP CASSEROLE

When you’re ready to share this luscious casserole, presentation and complementary sides can elevate the meal even further. A thoughtful pairing not only brings out the bold Cajun flavors but also rounds out the dining experience with fresh textures and vibrant contrasts. Below are four ideas that turn a simple weeknight dinner into a feast worth celebrating.

  • Fresh green salad

Toss crisp lettuce, cucumber ribbons, and cherry tomatoes with a zesty lemon vinaigrette. The bright acidity and crunchy greens cut through the creamy casserole, lightening each bite.

  • Crusty artisan bread

Warm slices of baguette or ciabatta brushed with garlic butter are perfect for soaking up any leftover creamy sauce. Serve in a bread basket and let guests tear off pieces as they please.

  • Steamed asparagus or green beans

A side of lightly steamed vegetables dressed with a drizzle of olive oil and a sprinkle of sea salt provides a fresh, green counterpoint, bringing balance to the rich main dish.

  • Chilled white wine

A crisp glass of Sauvignon Blanc or Pinot Grigio complements the shrimp’s sweetness and the dish’s spice level, making every forkful feel like a small celebration.

HOW TO STORE BAKED CREAMY CAJUN SHRIMP CASSEROLE

Whether you end up with leftovers or want to make it ahead for a dinner party, proper storage ensures that your creamy Cajun shrimp casserole stays as delicious as the day you baked it. Pay attention to temperature, airtight sealing, and reheating methods to preserve texture and flavor. Here are a few approaches to keep in mind:

  • Refrigerator storage

Allow the casserole to cool completely at room temperature (no more than two hours), then cover the baking dish tightly with foil or transfer portions to airtight containers. Store in the fridge for up to 3 days. Reheat individual servings in the microwave or warm the entire dish in a 350°F oven until heated through.

  • Freezer option

For longer-term storage, assemble the casserole (without baking), wrap the unbaked dish in plastic wrap and then foil, and freeze for up to one month. When you’re ready, thaw overnight in the refrigerator, remove the wrappings, and bake as directed.

  • Reheating tips

To prevent drying out, cover the casserole with foil when reheating. If using a microwave, add a splash of water or cream and cover with a microwave-safe lid to keep it moist.

  • Portion control

Consider dividing the casserole into individual ramekins before baking and storage. This makes reheating quick and easy, perfect for lunches or single servings without disturbing the rest of the dish.

CONCLUSION

What began as a craving for Southern flavors and creamy comfort has led us through a journey of colorful vegetables, boldly seasoned shrimp, and bubbling layers of cheese and rice. From gathering the key ingredients to mastering each step-by-step instruction, you’ve learned not only how to create a satisfying Baked Creamy Cajun Shrimp Casserole but also how to present it beautifully, store it intelligently, and enjoy it long after the oven has cooled. This casserole perfectly balances ease and excitement—an ideal recipe for beginner cooks and seasoned home chefs alike. Whether this becomes a family favorite for weeknight dinners or your new go-to dish for gatherings, it’s the kind of meal that brings people together and sparks conversations over every cheesy, spicy forkful.

Feel free to print this article or save it for later reference—your future self will thank you on those busy evenings when a quick, impressive dinner is needed. Below, you’ll find a FAQ section to tackle any lingering questions about substitutions, cooking times, or serving ideas. And of course, I’d love to hear from you! If you try this casserole, please share your experience, leave your comments, or ask any questions you have. Your feedback makes this kitchen community vibrant and helps fellow cooks embrace their own culinary adventures. Enjoy every bite, and happy cooking!

Baked Creamy Cajun Shrimp Casserole

Difficulty: Beginner Prep Time 20 mins Cook Time 30 mins Rest Time 10 mins Total Time 1 hr
Calories: 450

Description

Experience a blend of tender shrimp, colorful peppers, and creamy goodness baked to perfection. This casserole will tantalize your taste buds and warm your heart!

Ingredients

Instructions

  1. Preheat your oven to 350°F (175°C). Grease a 9x13-inch baking dish.
  2. In a medium bowl, toss the shrimp with olive oil and Cajun seasoning until well coated. Set aside.
  3. In a large skillet over medium heat, melt the butter. Add the chopped onion and minced garlic, and sauté until the onion becomes translucent.
  4. Stir in the red and green bell peppers and cook until they are soft, about 5 minutes.
  5. Add the frozen corn to the skillet and cook for an additional 2-3 minutes.
  6. Remove the skillet from heat and stir in the cream of mushroom soup and sour cream, mixing until well combined.
  7. Fold in the cooked rice, ensuring the mixture is evenly distributed. Season with salt and pepper to taste.
  8. Transfer half of the rice mixture to the prepared baking dish, spreading it evenly.
  9. Arrange the seasoned shrimp over the rice layer.
  10. Sprinkle half of the cheddar and Parmesan cheese evenly over the shrimp layer.
  11. Top with the remaining rice mixture and the rest of the cheeses.
  12. Cover the dish with foil and bake in the preheated oven for 20 minutes.
  13. Remove the foil and continue baking for an additional 10 minutes, or until the cheese is golden and bubbly.
  14. Once baked, let the casserole cool slightly before sprinkling with fresh parsley.
  15. Serve warm and enjoy your creamy Cajun shrimp casserole.

Note

  • For a spicier kick, add a pinch of cayenne pepper to the shrimp seasoning.
  • For added texture, consider mixing in a cup of cooked andouille sausage with the rice mixture.
  • This dish pairs well with a fresh green salad or crusty bread.
  • Leftovers can be stored in an airtight container in the refrigerator for up to 3 days.
Keywords: Cajun shrimp, creamy casserole, shrimp recipe, easy dinner, baked shrimp, comfort food

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Frequently Asked Questions

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Can I use frozen shrimp for this recipe?

Yes, you can use frozen shrimp for this casserole. Just make sure to thaw them properly before preparation. You can do this by placing them in the refrigerator overnight or running them under cold water until fully thawed. Once thawed, peel and devein the shrimp if not already done.

What can I substitute for cream of mushroom soup if I have dietary restrictions?

If you have dietary restrictions or simply prefer not to use cream of mushroom soup, you can substitute it with homemade creamy alternatives, such as a mixture of heavy cream and sautéed mushrooms or a dairy-free cream soup. Another option is to use a different cream-based soup like cream of celery or cream of chicken, depending on your preference.

How can I adjust the spice level of the casserole?

To adjust the spice level of the casserole, you can modify the amount of Cajun seasoning used in the dish. For a milder flavor, reduce the Cajun seasoning to 1/2 tablespoon. For additional heat, you can add a pinch of cayenne pepper to the shrimp seasoning or even increase the Cajun seasoning according to your taste preference.

Can I prepare this casserole in advance and reheat it later?

Yes, you can prepare the casserole in advance. Assemble it up to the point of baking, cover it tightly with foil or plastic wrap, and store it in the refrigerator for up to a day. When ready to bake, allow it to sit at room temperature for about 30 minutes, then proceed with the baking instructions. You can also store leftovers in an airtight container in the refrigerator for up to 3 days.

What sides pair well with this Baked Creamy Cajun Shrimp Casserole?

This casserole pairs well with a variety of sides. A fresh green salad with a light vinaigrette complements the richness of the dish, while crusty bread or garlic bread makes a great addition for sopping up the creamy sauce. You could also serve it with roasted vegetables or coleslaw for added texture and flavor.

Annie Delgado

Food and Lifestyle Blogger

Hi! I’m Annie Delgado, the home cook, storyteller, and flavor-lover behind CookingWithAnnie.com. Raised in a big Latin-American family where food was how we celebrated, connected, and showed love, I learned early on that cooking doesn’t have to be complicated to be meaningful.

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